Dr. Johannes Jungwirth is a key member of the Psychiatric University Hospital in Zürich, specializing in psychiatry and psychotherapy. His academic journey began at the Medical University of Vienna, where he pursued his medical degree, delving into neuroimaging and ketamine research. This work laid the groundwork for his profound interest in mental health. Dr. Jungwirth's professional focus as a senior physician is the treatment of patients with difficult-to-treat depression. In the « second opinion » consultation he offers interventional treatments such as rTMS, ECT, laughing gas, esketamine, MDMA and psilocybin. A noteworthy achievement in Dr. Jungwirth’s career is his pivotal role in establishing the first Compassionate-Use program for psychedelics at the Psychiatric University Hospital in Zürich. This initiative marks a significant milestone, positioning the clinic as one of the inaugural providers worldwide to offer psychedelic therapy outside the context of research studies. This program reflects Dr. Jungwirth’s dedication to making innovative treatments accessible to patients and a deep-seated desire to bridge the gap between cutting-edge research and real-world patient needs. His research has been instrumental in shedding light on how psilocybin-assisted therapy can enhance emotional empathy and social cognition in individuals with depression, contributing to the broader understanding of new treatment avenues.