This presentation takes a critical look at the fetishization of “connection” prevalent in psychedelic research.  “Connection” is a crucial term that some argue might be central to psychedelics’ transdiagnostic value (1) as well as its spiritual, social and ecological potentials (connection to the divine or “something bigger than oneself”, “pro-sociality” and “nature-relatedness”), the discursive affordances of “connection” in today’s context of networked capitalism remains dangerously underexplored. First and foremost, lacking is an interrogation of why precisely is all this connection needed to begin with – in other words, what drives the overwhelming sense of disconnection? Being multifaceted and widespread, the answer to this must be structural – one which I will explore through a Marxist-foucauldian framework emphasizing enclosure, competition, alienation, the “psy” sciences, and discipline. I will show how these processes impinge on the possibilities and challenges of contemporary psychedelia – for we must understand the deeper source of the problems these substances are summoned to treat or risk deploying them in such a way as to reinforce the latter. Specifically, I critically examine the hype around the paradigm-shifting potential psychedelic “connection” based on neurological or, more importantly, funghal metaphors – for these have long been intimately tied to the emergence of a networked form of capitalism (2,3) characterized as much by different pathologies of disconnection as much as by it global interconnectivity. It is precisely because psychedelic benefits coincide with the demands of this form of capitalism – openness, flexibility, emotional regulation – that we must remain critical of one-sided celebrations of connection (4).