This paper investigates how film aesthetics can be considered as means to create new understandings of the multiple transformations that humanity is currently experiencing under pressure of accelerating climate change and exponential developments in artificial intelligence. Might these technologies help us to ‘re-enchant’ nature as Michael Taussig suggests that we need to envision in what he calls ‘this age of meltdown’. Taussig’s notion of ‘mimetic excess’ where things come alive and ‘nature strikes back, every day more strange’, will be a guiding force into thinking what kind of conceptual ideas and ethical values are hidden in the aesthetics of contemporary films that can be considered as both posthuman and psychedelic (or ecodelic). Beyond the nature vs technology opposition, another crucial opposition seems to be undermined: that of fiction and nonfiction. Walter Benjamin’s ideas on technological perception and Stella Bruzzi’s concept of “approximation” will offer an approach to understand the deep entanglements of nature and artifice, fiction and nonfiction that will be addressed in reading two speculative fiction films, Annihilation (Alex Garland, 2018) and Vesper (Kristina Buožytė and Bruno Samper, 2022) in correlation with the imminent crises, emergencies  and transformations that the world-as-we-know-it faces today.